Wound Healing & Wounds

Physiology of wound healing

Wound healing starts with blood clotting to stop the bleeding and for provisionary wound closure. The exudation phase is characterized by inflammation and oedema. A fluid, the wound exudate, contains a variety of essential substances, e.g. enzymes, growth and cells necessary for an undisrupted healing process.


The regeneration and proliferation of new cells occurs in the granulation phase. The newly formed tissue fills in the wound from underneath and has a bright red appearance. Finally, the build-up of a new skin layer from the wound edges, epithelialization, completes the wound healing process and closes the wound.